Ultimate Guide to Hangovers

Author’s note*: This is a work in progress but there’s lots of information here if you still want to rummage through it.

As a society, we love to drink.

We all enjoy having fun with our friends so naturally we end up going out and partying while inevitably drinking a ton in the process. We just decide to willingly accept hangovers as being inevitable after a vivacious night of dancing our asses off.

We all understand the basic mechanics of how to be healthy.

Also, why those habits should be important in our life.

The main tenets are drilled into us such as eating well, exercising, meditation and stretching.  All of these should be a mainstay in our daily life.

Even if they are, we end up letting alcohol do its damage uncontrollably in our lives every time we drink.

We are just willing to let it run a muck without actually thinking about what it’s doing to us…

Why do Hangovers happen?

There are and were a few theories behind hangovers, the main one used to be dehydration. Everyone always says that, because it’s a logical leap to make after all. Since alcohol acts as a diuretic.

Long-story short, nobody knows exactly what causes hangovers. But we do know of quite a few factors that can intensify hangover symptoms. [http://www.eurekaselect.com/94052/article]

That’s what we hope to address in this current section. Almost undoubtedly you’ll always feel a lag the next morning after a night with alcohol versus without it.

However, by understanding all the factors that play into the severity of a hangover. We can aim to minimize the damage dealt and ease the short-term blows alcohol does and also give us more peace of mind when we think about our long-term health.

The Many Facets of a Hangover


This lil’ bugger has been said to be 10-30 times more toxic than alcohol itself.  I’m not exactly sure how the scientists really even got this number. But despite that, they’ve shown that acetaldehyde can cause vomiting, nausea, inflammation and pretty much everything that we identify with hangovers. [ https://www.ncbi.nlm.nih.gov/pubmed/15226168https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670145/ ]. It’s by far one of the simpler ones we have seem to have a bit of control over.


According to the Smithsonian:

“Most scientists believe that a hangover is driven by alcohol interfering with your body’s natural balance of chemicals in a more complex way. One hypothesis is that in order to process alcohol, your body must convert the enzyme NAD+ into an alternate form, NADH. With an excess buildup of NADH and insufficient quantities of NAD+, the thinking goes, your cells are no longer capable of efficiently performing a number of metabolic activities—everything from absorbing glucose from the blood to regulating electrolyte levels. But this hypothesis, too, has been contradicted by data: In studies, people with severe hangovers weren’t found to have lower levels of electrolytes or glucose in their blood.”

Also, this happens to be the mechanism behind how fatty-liver disease starts because of that accumulation of NADH it stops signaling for fatty acids to be oxidized. This buildup tricks your liver into thinking the needs have been met and people end up with cirrhosis(fancy name for fatty-liver).[https://www.ncbi.nlm.nih.gov/pubmed/15670660 ]

  Congeners // A possible cause of Hangovers?

Congeners are things found in alcohol that give it taste and aroma(or smell like rocket-fuel if you’ve ever had some ghetto moonshine). Things such as tannins, fusel alcohols, methane, esters and acetone.

A study was published in ‘Alcoholism: Clinical and Experimental Research‘  which was led by Professor Damaris Rohsenow over at Brown University. It used a sample size of 95 people and found that those who drank whiskey instead of vodka self-reported more symptoms that have to do with a hangover(such as nausea, headaches and irritability).

However, these people didn’t fare any worse on any of the cognitive assessments given to them versus the vodka group.

So it might be a wise idea to stick to clear liquors as much as possible to avoid the negative effects of congeners. You might not do worse on tests put forth by scientists, but you might have more of a chance of ending up feeling worse. Which is no good for you or those around you! [http://news.bbc.co.uk/2/hi/health/8416431.stm , https://onlinelibrary.wiley.com/doi/full/10.1111/j.1530-0277.2009.01116.x ]

  Diuretic // Dehydration

It’s no secret that alcohol dehydrates you.  Once you break the seal, the urination just doesn’t stop. What’s going on here seems to be one of the main reasons behind headaches. Although, there might be some other causes like Magnesium displacement[https://www.ncbi.nlm.nih.gov/pubmed/22426836]. Vasopressin(also known as ADH) happens to be the main culprit behind what causes us to urinate incessantly.

The Anti-Diuretic Hormone gets stopped by alcohol acting on your Thalamus and Pituitary gland. In turn causing the kidney to keep re-absorbing water. [https://science.howstuffworks.com/alcohol9.htm]

Excess urination leads to depletion of water soluble nutrients as well as limiting our supply of water being absorbed. It takes no leap of imagination that all that waterfalling our body does while drinking plays a role in how we feel the next day.

Women and Hangovers

Women also need to watch out, at least according to this danish study, women reported getting hangovers far more often than men. [http://sciencenordic.com/women-get-worst-hangovers]

Also, note here one of my favorite parts they highlight is this-
“Among women who drank without eating, 18 percent woke up with at least four symptoms of being hung over. But only 9 percent of women who drank and ate were hung over the following day.”

This can be a possible highlight to the importance of trying to get in some nutritional support while you drink.

I tend to lean toward the effect that carbohydrates have on helping the liver clear through toxins, and also if they focused on starchy foods more-so than protein based foods before bedtime to improve sleep quality[https://www.ncbi.nlm.nih.gov/pubmed/21349213/, https://www.ncbi.nlm.nih.gov/pubmed/573061/,https://www.ncbi.nlm.nih.gov/pubmed/17284739/]. We would most likely see the percentage of hungover women dr0op even more in women who ate some food + drank.


Sleep disruption in general causes problems for people such as irritability[https://www.ncbi.nlm.nih.gov/books/NBK19961/], stress[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4688585/], lack of healing[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1443671/], hormonal rhythm disruption[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377487/] and inflammation.

It’s my belief that sleep is one of the most potent healers period, and alcohol is definitely known to fuck up sleep. It’s impactful even after a minimal amount such as a couple night caps before bed. It’s most definitely the best practice to avoid alcohol late at night.. which is exactly the most fun time to use it, but that’s just not the reality of how we end up doing the alcohol in our society.

Since it’s not realistic, we need to look at things we can do to nutritionally enhance sleep and cover lost ground: supplements, and lifestyle habits such as exercise, meditation, yoga or basic stretches.  Use anything in your toolbox to help you de-stress to improve your  overall sleep duration and sleep quality. This is going to be a critical part in the process of avoiding cognitive decline caused by alcohol, both short-term and long-term.

You might not be nauseated or end up with a headache but you can still be hungover emotionally, intellectually and physically lagging easily the next day even if you don’t have the harshest and most annoying signs of a hangover.

So some things to keep in mind to improve over-all sleep, try inserting a daily mindful meditation practice and work your way up to 10-30 minutes a day, it has been shown to help with sleep disturbances plus plenty of other benefits. [https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2110998]

You might consider exercising right at the beginning of the day to help keep yourself circadially rhythmed, which will just improve your sleep patterns overall. This is a solid habit to have in general especially for those prone to insomnia.

Consider leaving early(to match up with your normal sleep patterns), which really isn’t always an option, and hardly ever happens for me.  But by far your best option is to try and keep your normal sleep schedule.

  Supplemental Sleep Control

It’s hard to beat rest. Part of the reason we believe hangovers cause so many issues is due to alcohol’s disruption of sleep and nutritional depletion might help curb some of those disruptions. Other than depletion of necessary b-vitamins, magnesium your blood-sugar can crash. Also another tool to add to your kit can be supplementing some melatonin sometime before bed.

Again, this might be easier to think of when you’re not drinking so some form of preparation can help ensure it, maybe setting an alarm or just putting the your nutrients out where you drink or carrying them in a purse/man purse/backpack. Get creative. It might just make work actually tolerable and maybe even enjoyable the next morning especially if you had an amazing night. 😉

While melatonin doesn’t seem to be a helpful solution for daily use, it can help in many acute situations[9]. Chris Kresser recommends .5-1mg of melatonin and suggests that some people find it more sedating in the lower dosages.

Magnesium calms the central nervous system and has been shown to be very effective in treating insomnia in a broad range of different people including alcoholics.

Magnesium can be a laxative, so for people with bowel issues, it’s best to use chelated forms to avoid any complications. Also with magnesium in the chelated form of magnesium-glycinate seems to be a good option since has also been shown help with sleep. [ https://www.ncbi.nlm.nih.gov/pubmed/22293292/ ] [.5-1 mg of melatonin depending upon body size] plus
[Try 200 mg of a Magnesium Chelate(glycinate) or Magnesium Citrate at bedtime]


  A Starchy Meal before Bedtime?

Have you ever gotten super hungry at the end of the night and ended up at the taco truck? Well, that’s just your body’s way of telling you what you need. Alcohol temporarily raises blood-sugar levels and causes elation and then afterwards it can result in a blood-sugar crash[].  This mechanism might also be why people start to develop alcoholism.  As a quick fix remedy to their low blood-sugar levels they’ll reach for the bottle and end up creating one of those vicious cycles of dependency.

The brain also uses a lot of energy while sleeping, and specifically during the REM cycle.[https://physoc.onlinelibrary.wiley.com/doi/full/10.1113/jphysiol.2010.197517] A starchy meal is an effective way of ensuring you get the energy your brain and liver need while sleeping. A lot of sleep is disrupted by alcohol’s effect on blood-sugar levels because of this crash it can cause you to wake up intermittently in the night because the liver does not have enough glycogen stored to ensure a good nights sleep.

Try to shoot for healthier food if possible, pizza might be the tastiest but it’s obviously not going to be optimal. Rice with vegetables is a great option or sweet potatoes are another amazing food to help you get more antioxidants and a myriad of other nutrients into your system.

Protein is fine but try to limit it, because it can compete with tryptophan making it less available to the pineal gland. One thing when it comes to maximizing carbohydrates over protein for sleep quality, is the fact that none of it play nearly as big of a factor as light exposure in terms of boosting melatonin production and stabilizing your circadian rhythms[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402070/].

Using red and orange lights at night time and limiting exposures to screens is very helpful in terms of improving sleep quality and a good all-around habit. Consider getting f.lux for your computer, twilight for android phones and changing the settings on your iPhone to block blue light exposure.

Back to the carbohydrate issue: Just make sure you’re getting yourself some healthy carbohydrates to minimize the impact of that blood-sugar crash.

Side tip: try adding sulfurous veggies like onions, garlics, leeks and broccoli or even mushrooms to the mix, your body needs amino acids made out of sulfur to help with glutathione production which will aid in lots of detoxification.

  Alcohol’s relationship with Stress

Stress is the other major component of alcohol’s deleterious effects, and most people aren’t going to give up social drinking, period. It’s probably most likely best to abstain and join the festivities from a sober perspective.

To me that’s a lot less fun, despite what the AA people might have to say about things. Anyhow, since most likely people in general aren’t going to give up alcohol, there are things you can do to minimize alcohol’s direct effects on stress and just over-all stress relieving things and they kinda link back into improving sleep, exercising,p nutrition and nutritional support through supplements… whodathunk?

Stress has a bunch of long term effects on the body, and also short term effects(think constant irritability over practically nothing) (source: ?.. how do i look that up? Good question). Stress can lead to inflammation, brain-inflammation, uh what the fuck do I know about stress.

Really not that much, I know a ton on how to manage it but I have no fucking idea about like stresses actual impact on the body, maybe stuff like c-reactive protein levels being raised(inflammation), headaches(?)/migraines(?).. being easily distracted/ADD/lack of focus when wanting it. Auto-immune diseases? Can stress lead to cancer?

Solutions Explain before we gave them several actionable steps, we want to teach them a few things*

  DHM // Possible Solution to Acetaldehyde

We’ve got a lot of facets to deal with when we’re trying to minimize the severity of hangovers and control their impact on our daily life.

alcohol itself as a toxin
sleep quality

The acetaldehyde while being a bit on over-hyped side, is a considerable toxin that’s probably one of the most manageable things we can actually control the easiest when it comes to hangover severity.

We need a properly functioning liver to get rid of it as fast as possible especially while we sleep so we can wake up hangover free. There are a bunch of elements to what makes a liver function well.  With today’s fast paced society and comfort based economy, we don’t treat our livers nearly as well as we should.

It’s not only alcohol that’s messing up our liver(it’s something or other and that or that, that i should look into but i got a general intuition that there’s a bunch of crap fucking up liver function). So we need a well functioning liver to clear out toxins in general, there’s not only acetaldehyde that causes disruption but also stuff like congeners found in darker alcohols, sugar overload from our infatuation with craft beer. (does sugar actually disrupt liver function? If so how??)

DHM has been shown to effectively take care of acetaldehyde, it used to be my reasoning to avoid it because acetaldehyde is also behind the euphoric effects of alcohol, but I think if you use DHM while drinking the amount of extra alcohol you’d have to drink to maintain the same buzz is going to be negligible after talking to people that have used it, plus I’ve heard it acts as a GABA re-uptake inhibitor(so think something like as it’s clearing out alcohol it acts like a very minor xanax minus the black-out part(people who know, know;)) and adds a lil extra chill to your step. (definite sources needed on this). DHM is an extract from a japanese fruit tree and it’s gained a lot of hype as a hangover thing that clears stuff out, but there’s a lot of other factors that go into hangovers but the main toxin causing the disruption is looking to be DHM. So if you want to nitpick the best time to pop DHM is probably best before bedtime but if you take it while drinking it should fare pretty well.

  Ginger // Nausea

So, we’ve got the other issue of nausea, it’s probably the most irritating aspect of hangovers in my opinion, it’s a toss up between headaches and nausea as the ones, but persistent gut rot can really weigh down your day like no other. So there’s really only one thing I know of that truly helps ease nausea and most likely prevent it quite a bit, and that’s ginger. It’s been shown with actual objective science (and in one instance alongside b6 specifically) to actually ease nausea in pregnant women and people with chemotherapy, I’m not aware of any studies on alcohol but those are really two big things that lead me to give a lot of props to ginger. There’s some issues regarding nausea in general behind alcohol, I haven’t seen much science as to what causes it, but I do know that even moderate drinkers and light drinkers have been shown to correlate with a thing called SIBO(Small intestinal bacterial overgrowth) and in my own personal experience it definitely seems like alcohol is feeding something in the small intestine, but after you get the nausea it seems to have no end, so the best real cause is prevention, but after that it’s really trying to minimize it’s impact. Ginger is really the best bet in that department but since the cause could be from both SIBO and acetaldehyde, being able to cure it in everyone for all bouts of drinking is a really tough feat, that being said, my best bet at the moment is using Ginger preemptively and after the fact. And probably using more than our product can offer(it’s hard enough to get people to take 4 pills in one sitting, so you’re best to steep some ginger tea and swallow the grounds if you got some real serious nausea the morning after and keep it coming, mischief manager does contain a proper amount of b6 though to at least sit alongside of it and work on fighting off that ginger…)

  Replenish Lost Nutrients

Alcohol is known to deplete a myriad of nutrients, whether it’s through it’s act of suppressing vasopressin, which is an anti-diuretic so you just end up peeing way too much after you break the seal and flush out all of your water soluble vitamins. Or it’s through wasting valuable resources to fight off toxins and reduce your inflammation(is there actual research for this or am I just talking about of my ass, I’m pretty sure this has to go down.. right?) So we’re looking at all your water solubles being flushed, your liver needing extra nutrient support to clear out toxins and also P.S. carbohydrates help immensely here(*ahem* to all you people that drink while doing ketogenesis).

Your liver might need specific b vitamins for Detox and also your liver is going to need things to build up the body’s master antioxidant glutathione. There are plenty of easy ways to boost glutathione so you can clear out the toxins quicker, and preferably while you sleep so you don’t wake up totally screwed.

  Magnesium Depletion

When researching nutrient depletion caused by alcohol I came across some research that stated that alcohol will force out magnesium[https://pubs.niaaa.nih.gov/publications/aa22.htm]. Which is bad news for a society that’s already tragically low on magnesium intake[https://www.ncbi.nlm.nih.gov/pubmed/22364157]. Please start eating leafy greens and dark chocolate ;).

In general it’s a really good idea to watch your Mg levels, but if you’re drinking it’s going to act a lot harsher on your system on top of an already uphill battle to get that vital magnesium which 300(and counting) systems of your body depend upon!

Magnesium has also been shown to help people get a better night’s sleep. That’s why you see natural calm everywhere, I don’t really recommend magnesium citrate myself, as it’s a saline laxitave, and you’re already starved for water if you’ve been drinking, picking an amino acid chelate- such as taurine which will also help your sleep out btw, but glycinate is probably my favorite daily form of magnesium and lastly you have magnesium malate as the popular forms of chelate(which is just a fancy way of saying the magnesium is bound to an amino acid making it easier to assimilate and not sucking all the water to your gut).

Vitamin B depletion

Extra B vitamins help with detoxification(how the fuck do they do that? Do they really boost glutathione). You end up peeing out a bunch of things essential to your body, but I think the thing that we’re reminded of most would have to be after we take those 5 hour energy drinks and pee out yellow.

Vitamin C: An abundant source of Antioxidants
Vitamin C is probably one fo the most powerful cheap effective allies that you can use while drinking. Sodium ascorbate happens to be a cheap form that’s easy on the stomach. You might consider adding a gram of sodium ascorbate for every 1 to 2 drinks that you take. Vitamin C is not only a precursor for collagen synthesis(you know to keep that skin glowing all pretty like) but it is also a a precursor to glutathione, it in of itself is an antitoxin and provides a very robust form of cheap electrons for donation to the your immune system and can help keep bacteria in check(that whole SIBO thing again).

Herbs, Adaptogens & Nootropics: Their role in your overall wellbeing as a drinker.

Adaptogens work on your body in two ways, they can either give you energy or help relax you, some lean more towards one way or the other and some go both ways depending on what you need to help restore balance. Sometimes being able to relax just a little bit can give you more energy in general and ability to focus. There are so many amazing adaptogens out there and they’re all currently being studied due to being used in ayurvedic, chinese and other traditioanl medicine for thousands of years.

Adaptogens work their magic unknowingly exactly by limiting the damage done to your body and mind by stress [https://examine.com/supplements/adaptogen/] and as a drinker, you’re going to want to have these guys on your side. Considering all the stress your body is put through after drinking, think about how you lag mentally and physically when you’re hungover- that’s no good.

So if you’re not going to quit drinking(which is almost certainly the most wisest, but hey I’m willing to sacrifice a lil time on the clock to enrich my time here on earth, and I think most people take that stance as well), you should think about equipping yourself with these guys and most likely daily, but you definitely want them to offset the damage done to you by alcohol here and there- there’s plenty of science proving their efficaciousness, these medicines usually have a long line of use- and the ancient people seemed to know what’s up and thankfully the science is catching up to the wisdom of those before us and people that are into this sorta stuff don’t have to be labeled woo woo salt lamp practitioners anymore.

One of my favorites happens to be Ashwagandha (Withania somnifera) is synergestic with alcohol, because it is GABAergic. Alcohol and stuff like Xanax, Valium, Klonopin, Temazepam etcetera all work on the GABA receptors, the nice thing about Ashwagandha though is, it’s most likely not going to make you mega blackout like if you took one of the pharmaceuticals and started drinking. Although it might not stop you from dumping all your pent up emotions on someone you just met an hour earlier.

This herb has been used in Ayurvedic medicine for a long time and has many many people really satisfied with it’s relaxing effects but can also help restore energy levels. Stress weighs you down, so it can be harder to have energy even if you seem high strung to others.

This root that got it’s name from it’s smell(it smells like a horse), is well-known amongst those who use it to reduce stress-related anxiety and if you’ve ever felt on edge after a long night out with minimal sleep, this is great. It’s also known for it’s ability to fight insomnia, and as I’ve tried to make a case for previously- anything to help improve sleep quality is really important for our body whether we drink or don’t drink, but especially if we do.

Amongst other things, this herb goes great with Milk Thistle to boost the Nrf2 gene activity, that’s good news for you as a drinker because Nrf2 gene is one of the main constituents that helps our body with detoxification pathways and as drinkers we all want to improve our detoxification when we’re taking in toxins that create more toxins such as acetaldehyde, that’s a lot of stress on the body. It’s main benefit as a companion for drinking and reducing the damage done by alcohol would most definitely be it’s stress reducing capability. The studies using extracts of it have shown significant decreases in stress and also anxiety.[https://www.ncbi.nlm.nih.gov/pubmed/21407960, https://www.ncbi.nlm.nih.gov/pubmed/23439798]

There’s also Panax Ginseng(also known as Korean Ginseng). Ginseng has been shown to boost the body’s 3 main antioxidant enzymes: Glutathione peroxidase, SOD(superoxide dismutase) and catalase.[https://www.ncbi.nlm.nih.gov/pubmed/21699953 / https://www.ncbi.nlm.nih.gov/pubmed/22805313]. *[it takes higher dosages than the average person really takes to achieve all 3 but, in dosages of 2g it’s shown to improve glutathione, and for drinkers that’s a good reason to want to have it on your side. The higher the dosage the more antioxidant potential, though.] There was a study that decided to look at arithmetic function and Ginseng(extract) supplementation and interestingly enough at the 200 mg dosage it slowed it down but at the 400 mg dosage arithmetic improved, but whether it slowed down math skills or enhanced them, it was noted that there was self-reported improvement in general well-being and calmness. [https://www.ncbi.nlm.nih.gov/pubmed/20737519] check this actual study if possible to make sure examine.com is properly stating what happened during it.

L-theanine as your sleeping partner
L-theanine is a super popular nootropic, and for good reason. One thing to make sure is that your product has L-theanine listed as an ingredient. In the studies that hyped Theanine as being so wondrous with it’s ability to effect Alpha wave stimulation(as in what happens after deeply meditating[possible link to a later more in depth article? Probably wise/best to make sure to re-read my own content that I create and go back over it and tie things together actively-remember to try and organize checking through content here and there to see if ideas arise and also fix things). Also we know sleep is super important for us, and this peculiar amino acid that was originally discovered in green tea might just be your ticket to catching a few higher quality sleep waves.

Theanine helps ease anxiety, and balance out caffeine intake. Speaking of that try to avoid those redbull ‘n vodkas if you’re out drinking. It might make the dancing better but it’s going to make your most important ally in fighting hangovers become super disrupted.

Sleep is super important for us. It’s found in green tea(camelia sinensis) and other than EGCG it’s suspected to be one of those things that makes green tea such a hyped ‘super food’ if we want to call it that, can we call tea a super food? ?

L-theanine helps ease anxiety, and can balance out caffeine intake.

Speaking of that try to avoid those redbull n vodkas if you’re out drinking. While those energy drinks might make your dancing better, it will also make your most important ally(sleep) in fighting hangovers become super disrupted.

Schisandra Berry (Shisandra Chinensis)

This popular adaptogen was well studied by the russians, and most likely for good reason but it’s really hard to get access to the full papers but from what is salvaged it had plenty of promise. And even better news, it’s synergestic with Panax Ginseng.

It’s effective at lowering cortisol levels in athletes, well high performance ones that is. Beginners not so much, it actually increased it. This could be a good thing in beginner athletes as having that stress hormone can give you a boost, cortisol is something that we need to wake up in the morning, without it we’d be just grumble and lollygag around until we got our much beloved coffee or tea).

Getting a cortisol boost in the morning can help reset our circadian rhythm cycle(thus improving sleep quality later that night. Plus hey we all know we get super athletic on the dance floor when we’re drinking with the right people, it basically brings out the inner professional athlete in all of us that we try and suppress ;).

But just the fact that it works well Ginseng by helping Shisandra Chinensis enhance its lignan absorption, is just another reason to add it to your drinking buddy stack.

It’s also known to increase the body’s anti-oxidative capacity. That’s good for us drinkers who end up causing a lot of oxidative stress on our body due to toxic build up and generally unhealthy night life. If we’re not dancing we’re just sitting there and not allowing our lymph nodes do to their jobs at clearing out crap(which is a good idea to try and stand around while drinking versus just sitting at the table puffing down cigs while crackin cold ones with the boys.

All of these things incrementally add up. There’s still a lot of science about Schizandra Berry out there, just not much in terms of human double blind clinical trials(the gold standard amongst most scientists). But I spent a lot of time digging into reading reviews and self reports and over and over people found so many great benefits it’s hard for me to pass this one by.

You’ll definitely want to keep this around though as it’s a very low risk, and potentially high reward. Just one more thing to stack into your life, drinks or no drinks. It’s powerful, and just dig around and do your own research. But I use it on a daily, and somewhat double or even triple down on it while I’m drinking. For the health oriented person, hangover or no hangover you want many things on your side. Nutrients, stress reducing practices, Neutraceuticals, Nootropics(aka brainfood, yummy)

::::: You may or may not have heard of something called hormesis. But this is very important. So the way Schisandra acts in such a way, which by the way Milk thistle and EGCG(from the prolific green tea aka camellia sinensis), they gently aggravate the system, and nudge it and ultimately make it more resilient. The best way to think about the hormetic effect is to think about how when you exercise, yeah it hurts and muscles break down. But ultimately they become bigger and stronger and you build resilience that is super-duper beneficial.

*a precautionary note to take into account- if you use wayfarin it might be best to avoid this or at least consult a doctor and keep everything test if you decide to use it.


Alongside with reducing nausea in a multitude of people ranging from pregnant women to chemotherapy patients, it’s actually been shown to help middle-aged women as a cognitive enhancer(it’s probably a safe bet that it enhances cognition in other people too). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3253463/

If you seem prone to hangovers, there might be something else going on there that is a warning, the nordic study I presented earlier hopes to address the issue of whether or not those who are more prone to hangovers are at more risk for developing diseases related to alcohol intake, it’s definitely a thought to take into consideration and whether or not it’s true.

I think as a conscientious drinker, you should always look toward minimizing the damage alcohol and hangovers can do. This can be done by taking actionable steps toward refueling your body with the nutrients  alcohol strips from you, and this practice should almost assuredly should help you in the long run.

After all, who doesn’t want to have less irritability or more ability to cope with stress?

I’m pretty we all would like smooth interactions with the people you surround yourself alongside having improved focus.


A fat soluble version of Vitamin B1(thiamine), which more easily crosses the blood brain barrier. This nutrient acts upon the dopamine receptors(at least that’s what it’s believed to do in humans, we haven’t proven it per se but there are plenty of people using higher dosages of it pretty safely, i believe they’ve run trials in dosages as high as 200mg in people with no serious adverse effects. That’s not to say jacking up your B1 levels with a fat soluble version(easily absorbed unlike water soluble versions that we end up peeing out most of the excess that your body doesn’t need.) might not be wise, but it can help you uptake vitamin B1 when you need it and it crossing the blood brain barrier is good news after depleting your body of your essential b vitamins. Thiamine is used to treat Thiamine is used to treat a brain disorder called Wernicke-Korsakoff Syndrome that is commonly seen amongst alcoholics. Thiamine use has been shown to help people with WKS while withdrawing from alcohol. (https://medlineplus.gov/druginfo/natural/965.html)

Milk Thistle
If you’re interested in protecting yourself from liver damage due to milk thistle you’ve no doubt heard about milk thistle. “According to the studies conducted at the Cancer Center of the University of Colorado, silibinin, which is an extract of milk thistle, has the ability to repair or kill skin cells that have been affected by the exposure to the UVB radiation. It also protects the skin against the damaging effects of UVB radiation.”


 5 simple steps that can help with a hangover

1. Try meditating in the morning it hangover or not, this will help you with a multitude of problems. Consider making it a daily task right upon waking or near it, especially after a night of drinking. Meditation has been shown to increase the gray-matter in your brain. [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3004979/]. “High alcohol consumption has been correlated with significant reductions in grey matter volume.” [http://www.sciencedirect.com/science/article/pii/S0149763415302451?via%3Dihub] [https://www.ncbi.nlm.nih.gov/pubmed/26072220]

2. Exercise in the morning to help reset your bunk circadian rhythms. Exercise has been shown to sort of reset our circadian rhythms and improve over all sleep quality the night following it. Consider jogging, doing some push ups, or some more intense yoga to wake you out of your slumber, even a bit of light exercise can increase focus, and if you can focus on what’s important it makes the sluggish effects of alcohol less magnified.

3. Use some ginger tea or a ginger supplement right away to help stave off any nausea that might be coming your way after a night of throwing down.

4. Make sure to drink some water with sea salt in it before even getting up. When we wake our mind will use up it’s salt reserves to help us balance right away so pre-loading with it before even standing up can help, plus it should go without saying that your going to be missing out on water, so drink it up, and hopefully drink some while drinking.

5. Make sure to eat breakfast, probably a more starchy one- these carbohydrates are necessary in terms of detoxification. Think about supplementing anything that could’ve been lost and also loading up on a bit of vitamin C for extra electron(is electron donation really how it works?) donation to aid your immune system that is getting beat up by alcohol. It’s my understanding that most toxins are lipid-soluble, and the liver needs carbohydrates and its derivatives to help breakdown the fat soluble toxins into become more soluble by water so you can excrete them from your body. *question to self: what solubility is acetaldehyde

Begin fighting hangover when you start drinking – What to do before bed.

Once again, try meditating if you can fit it in. If you can’t, then think about loading up on some healthy food to help fight against all the naughty things you did to your body. Those nutrients can make the difference, the carbohydrates, the b vitamins etcetera. Think about supplementing something that can improve your sleep quality such as l-theanine/magnesium/taurine. Try reading a book – meditating – stretching (even while you’re drinking).

What to do the next morning

Considering all of these things. One of the easiest companions you can add to your hangover defense is mischief manager. I might be a little biased since I formulated it, but ultimately I truly believe in it’s power, even if it didn’t prevent a hangover(which most of the time it does, unless you push the limits like I do, even then i’m still impressed at it’s ability to stop them) it helps replenish what is lost during a hangover and the adaptogens and nootropics within it help battle the stress and fatigue caused by alcohol, so it’s great as a drinking companion and great the morning after drinking. I personally take it every day(2 pills with a meal), but I might not recommend this to everyone because I’m unsure about how optimal sulbutiamine is as a daily nutrient, so if you choose to take it on the daily be warned I’m not sure jacking up the vitamin B1 levels that high is best in terms of longevity, but other than that you can use it as an extra boost and to help with liver function, cognitive boost, stress reduction. For the health oriented person, hangover or no hangover you want as much things on your side. Nutrients, stress reducing practices, neutraceuticals, nootropics, herbs and adaptogens are our ticket to being able to have our proverbial cake and eat it too.


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